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IUPUI chemist earns grant to improve drug screening in forensics

INDIANAPOLIS -- But in real life, mass spectrometry findings are less straightforward and slower paced. 

IUPUI analytical chemist Nicholas E. Manicke has received a $273,826 award from the U.S. Department of Justice's National Institute of Justice to improve the speed and accuracy of mass spectrometry for detecting drugs and poisons in blood samples. 

IUPUI mathematician receives major grant to model human motor movements for Huntington’s Disease research

INDIANAPOLIS – The three-year, $1.2 million grant is funded by the CHDI Foundation, a privately-funded, nonprofit biomedical research organization exclusively dedicated to Huntington’s disease. Molkov will receive about $380,000 over three years for the work.

Although the gene for Huntington's disease was identified in 1993 by the Huntington's Disease Collaborative Research Group, which included scientists from IUPUI, to date no way to stop or reverse the course of this devastating hereditary brain disorder has been discovered.

41 Science Students Named in Top 100 for 2015

INDIANAPOLIS -- “We are very proud of these Top 100 honorees,” said Dean Simon Rhodes. “They have taken full advantage of the integrated academic, research, leadership and community engagement opportunities that are uniquely found in the School of Science and at IUPUI.”

With 41 students on this year’s list, the School matches it record year in 2014. Last year, 12 of those were named among the Top 20 students on campus.

How alcohol hijacks brain's reward system: $545,000 award funds IUPUI investigation

INDIANAPOLIS -- Scientists have only a rudimentary understanding of how alcohol affects neurons in the brain. It is known that, as any addictive drug, alcohol directly or indirectly acts on a specific population of brain cells, called dopamine neurons. Through this action, the neurotransmitter dopamine is released, which evokes feelings of pleasure. However, the biological mechanisms of how alcohol evokes dopamine release have not been determined; exploring this question is the major goal of the grant.

IUPUI biologist receives NIH grant to study how glaucoma develops in stem cells

INDIANAPOLIS -- The five-year, $1.8 million grant is funded by the NIH’s National Eye Institute.

Glaucoma is a group of degenerative diseases that damage the eye's optic nerve and can result in vision loss and blindness. It is the most common disease that affects retinal ganglion cells. These cells serve as the connection between the eye and the brain. Once these cells are damaged or severed, the brain cannot receive critical information, leading to blindness.

$2.2M grant enables IUPUI to study depression-cardiovascular disease link in HIV patients

INDIANAPOLIS -- With the success of antiretroviral therapy, cardiovascular disease is now the leading cause of death in HIV-infected adults.

The four-year grant from the National Heart, Lung and Blood Institute to clinical health psychologist Stewart and the two other principal investigators -- infectious disease specialist Samir Gupta, M.D., associate professor of medicine in the IU School of Medicine, and internist Matthew Freiberg, M.D., associate professor of medicine in the Vanderbilt University School of Medicine -- supports two projects. 

IUPUI awarded $1.1 million grant to develop tools to predict physical appearance from DNA

INDIANAPOLIS -- Walsh's work, formally known as forensic DNA phenotyping, focuses on the prediction of externally visible characteristics such as eye, hair or skin color from genetic material.

Using DNA from biological samples such as blood, Walsh's new "DNA intelligence" tools will help forensic scientists determine physical appearance information. The tools will be especially useful in cases where conventional DNA profiling is non-informative and an investigation cannot move forward.

Geologist named fellow of Geological Society of America

Department of Earth Sciences faculty member Kathy Licht has been named fellow of the Geological Society of America in recognition of her contributions to the geosciences through research, teaching, publication and service. Licht is an associate professor in the Department of Earth Sciences at Indiana University-Purdue University Indianapolis.  

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